A Study of protective effect of Glycyrrhetinic acid in androgen induced alopecia
Androgenic alopecia is a common hair disorder of both gender but it is most prevalent in aged male. Glycyrrhiza glabra is a herb generally use to treat hair disorders and previous studies showed that petroleum ether extract of G.glabra possess hair growth promoting activity.In present study Glycyrrhetinic acid was isolated from G.glabra and was studied as curative agent for androgenic alopecia.
Male rats were taken for conducting studies on androgenic alopecia as they were made alopecic by injected with testosterone intramuscularly and protective effect was observed by Glycyrrhetinic acid and standard finasteride.
Results and discussion
The rat group on only testosterone developed alopecia while the animals on finasteride and Glycyrrhetinic acid along with testosterone do not developed alopecia. Thus this study proves protective effect of Glycyrrhetinic acid in androgen induced alopecia