Formulation and evaluation of fast disintegrating tablets of Granisetron HCl using natural polymers

Authors

  • Mohd Azharuddin, Danakka. Spandana Krishnananda Kamath, Subash. S. Pillai, A.R Shabaraya

Abstract

The present research work is to formulate and evaluate fast disintegrating tablets of Ganisetron HCl using natural polymers. Tablets were prepared by direct compression method using different drug polymer concentration. Fourier Transform Infrared Spectroscopy (FT-IR) study revealed no chemical interaction between drug and polymers used. Precompression and postcompression parameters were within the limits for the tablets. Disintegration and dissolution data of tablets were directly proportional to the superdisintegrants concentration. Selected fast dissolving tablet F8 containing plantago ovate 5%w/w has released 99.66 % within 3min.

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Published

28-10-2015

How to Cite

Krishnananda Kamath, Subash. S. Pillai, A.R Shabaraya, M. A. D. S. “Formulation and Evaluation of Fast Disintegrating Tablets of Granisetron HCl Using Natural Polymers”. Research in Pharmacy, vol. 1, no. 2, Oct. 2015, https://updatepublishing.com/journal/index.php/rip/article/view/211.

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