Effect of treatments with green tea on the levels of serum iron, total iron binding capacity and transferring saturation percentage in sera of rabbits with hyperprotenemia with induced diabetes mellitus

Abstract

In the present study the serum iron level (SI) and transferring saturated (Tsat%) were significantly increased(p<0.05) in rabbits with hyperproteinemia than control, while the total iron binding Capacity (TIBC) value was significantly decreased (p<0.05). In the second group diabetes mellitus (DM) also the SI level and Tsat% were significantly increased (p<0.05) than control before and after treatment with Green tea, while the (TIBC) values were significantly decreased (p<0.05) before and after treatment with Green tea. The (iron, TIBC and Tsat%) were significantly decreased after treatment with green tea (p<0.000). In the hyperproteinemia group, the total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG) were insignificant differences. While the low density lipoprotein cholesterol (LDL-C) was  significantly lower comparing with control. In the Diabetes Mellitus group, the TC, TG and vLDL, changes were insignificant, while LDL-C level was significantly increased and HDL –C level were significantly decreased in comparison with control. Malondialdehyde (MDA) levels in serum of rabbits with (DM) group before and after treated with green tea was significantly increased while changes in levels of MDA in hyperproteiemia and iron overload were insignificantly. The results indicated positive correlation between the levels of MDA and (HDL-C, LDL-C, Vit C, reduced serum glutathione (GSH), and uric acid (UA) and negative correlation in hyperproteinemia group. This study showed that (GSH) before and after 2 weeks treatment with green tea was significantly increased. While the rabbits left 1 month without treatment, the reduced glutathione was
significantly decreased in hyperproteinemia group (Hp).