Effect of Vinca minor on biochemical parameters using Wistar albino rats

  • Ininuma Helen Department of Biological Sciences (Microbiology Unit), Rhema University, Aba, Nigeria
  • Winner Kalu Department of Chemical Sciences (Biochemistry Unit), Rhema University, Aba, Nigeria
  • Onyeabo Chimaroke, Odika Prince Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria

Abstract

Effect of Vinca minor on biochemical parameters using Wistar albino rats was investigated to ascertain the plant`s haematotoxicity, liver and kindey tissue damage potential. Haematological indices and markers of liver and kidney for cellular integrity were monitored in rats given different concentrations of leaf extract of V.minor. Results obtained showed significant reduction (p<0.05) in PCV and Hb of test rats against the control. Test rats also had significant increase (p<0.05) in liver enzymes and marked significant (p<0.05) reduction in urea and some electrolytes in test rats when compared to control. The loss of integrity of the liver cells, retention of the urea and some electrolytes in the kidney would certainly lead to a possible disease condition with time. This study has shown the effect of V.minor on biochemical parameters using Wistar albino rats.

Keywords: Vinca minor, haematology, liver enzymes, kidney function.

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References

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