Van der woude syndrome- a case report

Abstract

Van der Woude syndrome (VWS) is a rare, autosomal dominant disorder, caused by deletions in the chromosome band 1q32-q41, and characterized by cleft lip or cleft palate, distinctive pits of the lower lips, or both. The most prominent and consistent features of Van der Woude syndrome are oro-facial defects. The oro-facial abnormalities include lower lip pits alone, hypodontia, or isolated cleft lip and cleft palate of varying severity. A case of Van der Woude syndrome, with the typical manifestations in a seven year old male patient is being presented, along with its review of literature.