A Comparative Antipyretic Activity of the Crude Extracts of the Ariel Parts of Glycosmis pentaphylla and Bauhinia variegata

Authors

  • Mandal S2*, Upadhyay N1, Sharma I1, Rohit S1, Mandloi A1

Abstract

This study indicates that Glycosmis pentaphylla and Bauhinia variegata extracts have good antipyretic activity. Ethanolic extract of Bauhinia variegata and Glycosmis pentaphylla exhibited significant anti-pyretic activities in Brewer’s yeast induced pyrexia in rats. The maximum antipyretic activity throughout the test period of 6 hours was produced by ethanolic extract of plant Glycosmis pentaphylla (200 mg/kg) and standard (paracetamol treated) group. In general, non-steroidal anti-inflammatory drugs produce their antipyretic action through the inhibition of prostaglandin synthetase within the Hypothalamus. Therefore, the antipyretic activity of extracts of Bauhinia variegata and Glycosmis pentaphylla is probably by inhibition of prostaglandin synthesis in hypothalamus.

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Published

26-04-2011

How to Cite

Rohit S1, Mandloi A1, M. S. U. N. S. I. (2011). A Comparative Antipyretic Activity of the Crude Extracts of the Ariel Parts of Glycosmis pentaphylla and Bauhinia variegata. Recent Research in Science and Technology, 3(7). Retrieved from https://updatepublishing.com/journal/index.php/rrst/article/view/729

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Articles