Clinical Evaluation of Oxidative Stress in Women with Breast Cancer

  • G. Krishna Veni, D. Bhaskar Rao, D. Muni Kumar, B. Usha, V. Murali Krishna, T. Raghava Rao*

Abstract

Breast cancers are potentially life-threatening malignancies in women. Development of cancer produces oxidative stress, which increases with disease progression. Hence, studies on antioxidants may be the most promising area of research for this clinical menace. We analysed serum Uric acid (UA) and Bilirubin (BR) in women with breast cancer. The changes in the levels of serum uric acid and bilirubin are measured in breast cancer patients to assess the oxidative stress. A significant increase in the levels of uric acid and an insignificant increase in the levels of bilirubin was observed in all the three categories of breast cancer patients compared to normal individuals. The results suggested that high ROS production supports the oxidative stress in breast cancer. So, the treatment with antioxidants in the initial stages of the disease may be useful as secondary therapy.

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Author Biography

G. Krishna Veni, D. Bhaskar Rao, D. Muni Kumar, B. Usha, V. Murali Krishna, T. Raghava Rao*
Department of Biochemistry, Andhra University
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How to Cite
Muni Kumar, B. Usha, V. Murali Krishna, T. Raghava Rao*, G. K. V. D. B. R. D. “Clinical Evaluation of Oxidative Stress in Women With Breast Cancer”. Recent Research in Science and Technology, Vol. 3, no. 1, Dec. 2010, https://updatepublishing.com/journal/index.php/rrst/article/view/578.
Section
Health Sciences