A Single Blind In vitro UV Spectrophotometry Quantitative Assay of Different Pharmaceutical Oral Preparartion of 500mg Metformin

Authors

  • K.Latha1*, Sheela D2, Tharini C B3

Abstract

Aim: To find out the chemical equivalence of metformin 500mg of five different manufacturers. Materials and methods: Quantitative analysis of five different brand of metformin 500mg was done by spectrophotometry. The reproducibility was tested. Throughout the study quantitative analyst was kept blind of the product. Results: The results were analysed to find out the chemical equivalence of metformin 500mg. It was found to be chemically equivalent. Conclusion: The above study revealed the assay purity of metformin 500mg of five different brands, to that of Indian pharmacopoeia prescribed standards.

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Author Biography

K.Latha1*, Sheela D2, Tharini C B3

1Assistant Professor, Department of Pharmacology, Saveetha Medical College & Hospital, Saveetha University, Saveetha Nagar, Thandalam, CHENNAI – 602 105, T.N, India2Post Graduate Student, Department of Pharmacology, Saveetha Medical College & Hospital, Saveetha University, Saveetha Nagar, Thandalam, CHENNAI – 602 105, T.N, India3Professor & Head, Department of Pharmacology, Saveetha Medical College & Hospital, Saveetha University, Saveetha Nagar, Thandalam, CHENNAI – 602 105, T.N, India  

Published

15-12-2010

How to Cite

Sheela D2, Tharini C B3, K. (2010). A Single Blind In vitro UV Spectrophotometry Quantitative Assay of Different Pharmaceutical Oral Preparartion of 500mg Metformin. Recent Research in Science and Technology, 2(11). Retrieved from https://updatepublishing.com/journal/index.php/rrst/article/view/543

Issue

Volume 2, Issue 11, 2010

Section

Pharmacy & Pharmacology