Hepatoprotectivity and an Antioxidant Study of Ipomoea hederacea on Experimentally Induced Hepatotoxic Rats

Authors

  • Ruckmani Devi S1, M. Chitra2 and P. Jaya mathi1*

Abstract

Ipomoea hederacea extract, a novel hepatoprotective drug has been shown to provide an antioxidant potential against carbon tetra chloride treated experimentally induced hepatotoxitic rats in comparison with standard hepatoprotective drug silymarin. Significantly raised levels of serum bilirubin, lipid peroxides and decreased activities of antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and  decreased activities of gamma glutamyl transpeptidase were observed and it was nearer to  normal in Ipomoea hederacea administrated experimentally induced hepatotoxic rats. These observations clearly suggested the hepatoprotectivity and antioxidant property of Ipomoea hederacea.

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Author Biography

Ruckmani Devi S1, M. Chitra2 and P. Jaya mathi1*

1Lecturer in Biochemistry, 2Professor in Biochemistry, S.T.E.T. Womens College, Mannargudi *Professor in Biochemistry, 1*Department of Biochemistry, Meenakshi Ammal Dental College, Meenakshi Academy of Higher Education and Research, Alapakkam main Road, Chennai-600095. Tamil Nadu, India

Published

15-12-2010

How to Cite

mathi1*, R. D. S. M. C. and P. J. (2010). Hepatoprotectivity and an Antioxidant Study of Ipomoea hederacea on Experimentally Induced Hepatotoxic Rats. Recent Research in Science and Technology, 2(11). Retrieved from https://updatepublishing.com/journal/index.php/rrst/article/view/540

Issue

Section

Biochemistry