Mosquito Proteomics: Present and Future Prospective

Abstract

Proteomics isthe detailed study of protein structure, function and protein-proteininteraction. In the few last years a lot of research work has been done in  genomes and transcriptomes by using highthroughput methods of analysis to understand the cellular functions. But nowthere is limited scope in the field of genomics and hence there is rapid moveto the proteomics. Proteomics is an integral part of system-level analysis ofcellular functions, promising to shed light on regulatory mechanisms that are beyondthe reach of genomics and transcriptomics. Proteomics is a rapidly evolving field due to advancements in thetechniques of identification of proteins by MS-spectrometry,  improvements in methods of protein-proteininteraction analysis, development of high-throughput approaches to synthesizeand purify proteins for microarray and crystallography applications. Currentproteomics approaches not only identify proteins expression, but alsoprotein-protein interactions and post-translational modifications. In thepresent review an attempt has been made to study proteomics analysis inmosquitoes.Key words: Anopheles, Aedes, Culex, Protein expression etc.