In-vitro anti-inflammatory and antioxidant potential of Triphala guggul tablets

  • Poonam Verma Lala Lajpat Rai College of Pharmacy, Near P. S. Sadar, Moga-142001, Punjab, India
  • Baljinder Singh Lala Lajpat Rai College of Pharmacy, Near P. S. Sadar, Moga-142001, Punjab, India
  • Arun Kumar Baba Farid College of Pharmacy, Mor Karima, Mullanpur, Ludhiana- 142023, Punjab, India
  • Ruchita Sharma Ex-PG Scholar, University Institute of Pharmaceutical Sciences and Research, BFUHS, Faridkot-151203, Punjab, India
  • Vijender Kumar University Institute of Pharmaceutical Sciences and Research, BFUHS, Faridkot-151203, Punjab, India

Abstract

Current study investigated the in-vitro anti-inflammatory and antioxidant potential of successive extracts of a polyherbal formulation Lakshadi guggul tablet a combination of Indian medicinal plants viz. Commiphora mukul, Cissus quadrangularis, Laccifer lacca, Sida veronicaefolia, Terminalia arjuna and Withania somnifera. The studies were undertaken to assess the anti-inflammatory at doses levels of 200 mg and 400 mg/ml of each extract by in-vitro red blood cells membrane stabilization and antioxidant potential at doses levels of 125 μg, 250 μg and 500 μg/ml of each extract by DPPH free radical scavenging activity methods. In-vitro anti- inflammatory activity of extracts were found significant (aP<0.01, bP<0.05) red blood cells membrane stabilization effects with 66.40 % in methanol, 62.15 % in ethyl acetate, 59.39 % in chloroform extract, and 66.18% with standard drug diclofenac. Similarly, in-vitro antioxidant activity of Lakshadi guggul tablets extracts were found significant reduction in free radical scavenging activity in 49.60% in methanol, 48.10% in ethyl acetate extract and relatively similar to 52.21% of standard drugs. The results of these studies revealed that Lakshadi guggul have strong potential antioxidant and anti- inflammatory agents.

Keywords: Lakshadi guggul, in-vitro, anti-inflammatory, antioxidant, diclofenac etc.

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How to Cite
Verma, P., B. Singh, A. Kumar, R. Sharma, and V. Kumar. “In-Vitro Anti-Inflammatory and Antioxidant Potential of Triphala Guggul Tablets”. Journal of Medicinal Herbs and Ethnomedicine, Vol. 6, May 2020, pp. 45-47, doi:https://doi.org/10.25081/jmhe.2020.v6.6238.
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Research Article

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