Chemical composition and antioxidant activity of the crude methanolic extracts of Mentha spicata

Authors

  • J Rameshwar Naidu Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.
  • R B Ismail Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.
  • Chen Yeng Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.
  • S Sasidharan Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.
  • Kumar P Department of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong-08100, Kedah, Malaysia.

Keywords:

Alocacia Mentha spicata, GC-TOFMS, chemical profiling, antioxidant activity

Abstract

The chemical constituents and antioxidant activity of the crude extracts of Mentha spicata were investigated. Phytochemical analysis indicated the presence of sugar, flavonoids and alkaloids in the crude extracts of Mentha spicata. GC-TOFMS (Gas Chromatography Time-of-Flight Mass Spectrometry) analysis indicated the presence of fatty acid methyl esters (hexa decane, hepta decane, octa decane) terpenoids, terpenoid alcohol, caryophyllene and glycosides. Total phenolic components of the crude extracts was found to be 27.26±0.62 mg/g gallic acid equivalent which was determined by Folin-Ciocalteu method. The DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity was found to increase with increasing concentrations and  was found to be 54.84±0.57% with an IC50 value of 25.2µg/ml. The reported antioxidant activity may be due to the presence of flavonoids and fatty acid methyl esters which has the scavenging potential by reducing the free radicals.  

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Author Biographies

J Rameshwar Naidu, Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

R B Ismail, Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

Chen Yeng, Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

S Sasidharan, Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

Institute for Research in Molecular Medicine (INFORMM), University Science Malaysia, 11800, Penang, Malaysia.

Kumar P, Department of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong-08100, Kedah, Malaysia.

Department of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong-08100, Kedah.Malaysia.

Published

13-03-2012

How to Cite

Rameshwar Naidu, J., Ismail, R. B., Yeng, C., Sasidharan, S., & P, K. (2012). Chemical composition and antioxidant activity of the crude methanolic extracts of Mentha spicata. Journal of Phytology, 4(1). Retrieved from https://updatepublishing.com/journal/index.php/jp/article/view/2753

Issue

Volume 4, Issue 1, 2012

Section

Research Article