Antioxidant potentials of the extracts from 14 selected medicinal plants

Antioxidant capacity and importance

  • Alev Önder Department of Pharmacognosy, Faculty of Pharmacy, Ankara University, Ankara, Turkey
  • Ahsen Sevde Çinar Department of Pharmacognosy, Faculty of Pharmacy, Ankara University, Ankara, Turkey and Department of Pharmaceutical Botany/Pharmacognosy,Faculty of Pharmacy, Lokman Hekim University, Ankara, Turkey
  • Gülsüm Gençaslan Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkey
  • Tülay Çoban Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkey

Abstract

Most of the medicinal plants possess interesting antioxidant properties. The present study aimed to evaluate the antioxidant capacity of some medicinal plants from Turkey, such as Anthemis tinctoria L. (Compositae), Inula britannica L. (Compositae), Malabaila secacul Banks & Sol (Apiaceae), Zosima absinthifolia (Vent) Link (Apiaceae), Thymus sipyleus Boiss. (Lamiaceae), Phlomis armeniaca Willd. (Lamiaceae), Sideritis galatica Bornm. (Lamiaceae), Sedum acre L. (Crassulaceae), Potentilla erecta Uspenski ex Ledeb. (Rosaceae), Digitalis lamarckii Ivan (Scrophulariaceae), Glaucium grandiflorum Boiss. & Huet var. grandiflorum (Papaveraceae), Fumaria asepala Boiss. (Papaveraceae), Centranthus longiflorus Stev. (Valerianaceae), Allium rotundum L. (Amaryllidaceae). The ethyl acetate and methanol extracts of the 14 species were screened by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, superoxide anion (SO) radical scavenging, and lipid peroxidation (LPO) assays. The methanol and ethyl acetate extracts of Potentilla erecta have the highest DPPH scavenging activity (IC50=0.014 and 0.03 mg/mL, respectively). The maximum inhibition of LPO has been exhibited by ethyl acetate extract of Glaucium grandiflorum var. grandiflorum (IC50=0.34 mg/mL) followed by methanol extracts of T. sipyleus (IC50=0.38 mg/mL). The methanol extract of A. rotundum demonstrated the highest SO activity (IC50=0.11 mg/mL). In conclusion, these extracts have a high potential for antioxidant activity may be considered to use free radical-related diseases.

Keywords: Antioxidant, DPPH, extract, lipid peroxidation, plants, superoxide

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How to Cite
Önder, A., A. Çinar, G. Gençaslan, and T. Çoban. “Antioxidant Potentials of the Extracts from 14 Selected Medicinal Plants”. Journal of Medicinal Herbs and Ethnomedicine, Vol. 6, Feb. 2020, pp. 17-20, doi:https://doi.org/10.25081/jmhe.2020.v6.6060.
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Research Article