Myocardial infarction protective effect of xyloglucan on Drosophila melanogaster: A review

Authors

  • K. M. Monisha Division of Molecular Biology, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru-570015, Karnataka, India
  • A. S. Dhanu Division of Molecular Biology, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru-570015, Karnataka, India
  • T. S. Gopenath Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru-570015, Karnataka, India
  • N. Pandeeswari Department of Microbiology, Faculty of Agriculture, Annamalai University, Annamalai Nagar-608002, Tamil Nadu
  • G. G. Swamy Department of Pathology, Faculty of Medicine and Health Sciences, Quest International University, Malaysia
  • Karthikeyan Murugesan Department of Microbiology, Faculty of Medicine and Health Sciences, Quest International University, Malaysia
  • Anjuna Radhakrishnan Department of Microbiology, Faculty of Medicine and Health Sciences, Quest International University, Malaysia
  • Uthamalingam Murali Department of Surgery, Manipal University College Malaysia, Malaysia
  • Boojhana Elango Department of Microbiology, Muthayammal College of Arts and Science, Rasipuram, Namakkal-637408, Tamil Nadu, India
  • Kanthesh M. Basalingappa Division of Molecular Biology, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru-570015, Karnataka, India
  • Maghimaa Mathanmohun Department of Microbiology, Muthayammal College of Arts and Science, Rasipuram, Namakkal-637408, Tamil Nadu, India

DOI:

https://doi.org/10.25081/jes.2023.v14.8729

Keywords:

Myocardial infarction, Xyloglucan, Drosophila melanogaster, Notch signaling pathway

Abstract

Myocardial infarction, more often known as cardiac arrest, occurs when the supply of blood to the heart’s coronary artery decreases or ceases, causing damage to the heart muscle. Xyloglucan is a plant polysaccharide. Xyloglucan has been proven in several studies utilizing model organisms to reduce the risk of coronary heart disease by avoiding post-occlusion phases inhibiting apoptosis and enhancing energy metabolism. Many studies utilize Drosophila melanogaster because its SRY-related HMG-box 5 (SOX5) gene encodes a SOX family transcription factor; the human SOX5 ortholog, Sox102F, is well conserved in Drosophila melanogaster. Suppressing Sox102F in flies resulted in significant heart dysfunction, structural defects, and a disturbance in notch signal transduction. This demonstrates that SOX5 serves an important functional part in the heart and that variations in SOX5 concentrations may contribute to the possibility of myocardial infarction. Xyloglucan activity is significant in myocardial infarction and may be lowered in the myocardium after H/R damage by stimulating Notch signaling, which may benefit myocardial survival, angiogenesis, and cardiac function. This review discusses the roles of the human SOX5 and Drosophila SOX102F genes, the notch signaling system, and how xyloglucan in tamarind seeds may defend against heart damage by preventing apoptosis along with improving energy metabolism.

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References

Arshad, M. S., Imran, M., Ahmed, A., Sohaib, M., Ullah, A., Nisa, M. U., Hina, G., Khalid, W., & Rehana, H. (2019, November). Tamarind: A diet‐based strategy against lifestyle maladies. Food Science and Nutrition, 7(11), 3378–3390. https://doi.org/10.1002/fsn3.1218

Berg, D. D., Wiviott, S. D., Braunwald, E., Guo, J., Im, K., Kashani, A., Gibson, C. M., Cannon, C. P., Morrow, D. A., Bhatt, D. L., Mega, J. L., O’Donoghue, M. L., Antman, E. M., Newby, L. K., Sabatine, M. S., & Giugliano, R. P. (2018). Modes and timing of death in 66 252 patients with non-ST-segment elevation acute coronary syndromes enrolled in 14 TIMI trials. European Heart Journal, 39(42), 3810-3820. https://doi.org/10.1093/eurheartj/ehy556

Chen, H., Jiang, X., Li, S., Qin, W., Huang, Z., Luo, Y., Li, H., Wu, D., Zhang, Q., Zhao, Y., Yu, B., Li, C., & Chen, D. (2020). Possible beneficial effects of xyloglucan from its degradation by gut microbiota. Trends in Food Science and Technology, 97, 65-75. https://doi.org/10.1016/j.tifs.2020.01.001

de Celis, J. F., & García-Bellido, A. (1994, May 1). Roles of the Notch gene in Drosophila wing morphogenesis. Mechanisms of Development, 46(2), 109-122. https://doi.org/10.1016/0925-4773(94)90080-9

Deng, D., Liu, L., Xu, G., Gan, J., Shen, Y., Shi, Y., Zhu, R., & Lin, Y. (2018). Epidemiology and serum metabolic characteristics of acute myocardial infarction patients in chest pain centers. Iranian Journal of Public Health, 47(7), 1017-1029.

Dong, X., Zhou, M., Li, Y., Li, Y., Ji, H., & Hu, Q. (2021, November 18). Cardiovascular protective effects of plant polysaccharides: A review. Frontiers in Pharmacology, 12, 783641. https://doi.org/10.3389/fphar.2021.783641

Frangogiannis, N. G. (2015). Pathophysiology of myocardial infarction. Comprehensive Physiology, 5(4), 1841-1875. https://doi.org/10.1002/cphy.c150006

Kachanova, O., Lobov, A., & Malashicheva, A. (2022). The role of the Notch signaling pathway in recovery of cardiac function after myocardial infarction. International Journal of Molecular Sciences, 23(20), 12509. https://doi.org/10.3390/ijms232012509

Li, A., Ahsen, O. O., Liu, J. J., Du, C., McKee, M. L., Yang, Y., Wasco, W., Newton-Cheh, C. H., O’Donnell, C. J., Fujimoto, J. G., Zhou, C., & Tanzi, R. E. (2013). Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography. Human Molecular Genetics, 22(18), 3798-3806. https://doi.org/10.1093/hmg/ddt230

Li, A., Hooli, B., Mullin, K., Tate, R. E., Bubnys, A., Kirchner, R., Chapman, B., Hofmann, O., Hide, W., & Tanzi, R. E. (2017). Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment. Human Molecular Genetics, 26(8), 1472-1482. https://doi.org/10.1093/hmg/ddx051

Li, Y., Hiroi, Y., & Liao, J. K. (2010). Notch signaling as an important mediator of cardiac repair and regeneration after myocardial infarction. Trends in Cardiovascular Medicine, 20(7), 228-231. https://doi.org/10.1016/j.tcm.2011.11.006

Lim, S. H., & Lee, J. (2017). Xyloglucan intake attenuates myocardial injury by inhibiting apoptosis and improving energy metabolism in a rat model of myocardial infarction. Nutrition Research, 45, 19-29. https://doi.org/10.1016/j.nutres.2017.07.003

Lim, S. H., Kim, Y., Yun, K. N., Kim, J. Y., Jang, J. H., Han, M. J., & Lee, J. (2016). Plant-based foods containing cell wall polysaccharides rich in specific active monosaccharides protect against myocardial injury in rat myocardial infarction models. Scientific Reports, 6, 38728. https://doi.org/10.1038/srep38728

MacGrogan, D., Münch, J., & de la Pompa, J. L. (2018, November). Notch and interacting signaling pathways in cardiac development, disease, and regeneration. Nature Reviews Cardiology, 15, 685-704. https://doi.org/10.1038/s41569-018-0100-2

Mishra, A., & Malhotra, A. V. (2009). Tamarind xyloglucan: A polysaccharide with versatile application potential. Journal of Materials Chemistry, 19(45), 8528-8536. https://doi.org/10.1039/b911150f

Nguyen, T. T., Jittanit, W., & Srichamnong, W. (2019). Production of xyloglucan component extracted from tamarind (Tamarindus indica) seeds using microwave treatment for seed decortication. Journal of Food Processing and Preservation, 43(8), e14055. https://doi.org/10.1111/jfpp.14055

Nistri, S., Sassoli, C., & Bani, D. (2017). Notch signaling in ischemic damage and fibrosis: Evidence and clues from the heart. Frontiers in Pharmacology, 8, 187. https://doi.org/10.3389/fphar.2017.00187

Pfeufer, A., van Noord, C., Marciante, K. D., Arking, D. E., Larson, M. G., Smith, A. V., Tarasov, K. V., Müller, M., Sotoodehnia, N., Sinner, M. F., Verwoert, G. C., Li, M., Kao, W. H., Köttgen, A., Coresh, J., Bis, J. C., Psaty, B. M., Rice, K., Rotter, J. I., . . . Heckbert, S. R. (2010, February). Genome-wide association study of PR interval. Nature Genetics, 42, 153-159. https://doi.org/10.1038/ng.517

Reed, G. W., Rossi, J. E., & Cannon, C. P. (2017). Acute myocardial infarction. The Lancet, 389(10065), 197-210. https://doi.org/10.1016/S0140-6736(16)30677-8

Singh, N. K., Baranwal, J., Pati, S., Barse, B., Khan, R. H., & Kumar, A. (2023, March 27). Application of plant products in the synthesis and functionalization of biopolymers. International Journal of Biological Macromolecules, 237, 124174. https://doi.org/10.1016/j.ijbiomac.2023.124174

van de Vegte, Y. J., Tegegne, B. S., Verweij, N., Snieder, H., & van der Harst, P. (2019). Genetics and the heart rate response to exercise. Cellular and Molecular Life Sciences, 76, 2391-2409. https://doi.org/10.1007/s00018-019-03079-4

Wu, F., Yu, B., Zhang, X., & Zhang, Y. (2017). Cardioprotective effect of Notch signaling on the development of myocardial infarction complicated by diabetes mellitus. Experimental and Therapeutic Medicine, 14(4), 3447-3454. https://doi.org/10.3892/etm.2017.4932

Yamatoya, K., Shirakawa, M., & Baba, O. (2000). Effects of xyloglucan on lipid metabolism. Inhydrocolloids (pp. 405-410). Elsevier Science.

Zhang, Q., Wang, L., Wang, S., Cheng, H., Xu, L., Pei, G., Wang, Y., Fu, C., Jiang, Y., He, C., & Wei, Q. (2022, March 10). Signaling pathways and targeted therapy for myocardial infarction. Signal Transduction and Targeted Therapy, 7, 78. https://doi.org/10.1038/s41392-022-00925-z

Zhou, X. L., Zhu, R. R., Liu, S., Xu, H., Xu, X., Wu, Q. C., & Liu, J. C. (2018, August). Notch signaling promotes angiogenesis and improves cardiac function after myocardial infarction. Journal of Cellular Biochemistry, 119(8), 7105-7112. https://doi.org/10.1002/jcb.27032

Published

26-12-2023

How to Cite

Monisha, K. M., A. S. Dhanu, T. S. Gopenath, N. Pandeeswari, G. G. Swamy, K. Murugesan, A. Radhakrishnan, U. Murali, B. Elango, K. M. Basalingappa, and M. Mathanmohun. “Myocardial Infarction Protective Effect of Xyloglucan on Drosophila Melanogaster: A Review”. Journal of Experimental Sciences, vol. 14, Dec. 2023, pp. 1-5, doi:10.25081/jes.2023.v14.8729.

Issue

Volume 14, 2023

Section

Articles