Comparative Antinociceptive Study of Leaf, Bark and Seed Extracts of Neem Collected from Aligarh District
Abstract
Azadirachta indica (family Meliaceae) is commonly known as neem. The latinized name of neem A. indica (in Persian, Azadi = free, diracht = tree) literally meaning “the free tree of Indiaâ€Â, is an alliteration for its being intrinsically free from insect and disease problems. The neem tree is considered as a ‘sarvaroga nivarini’ (the panacea for all diseases) and has also been hailed as ‘heal all’, ‘divine tree’, ‘village dispensary’ and ‘nature’s drugstore’. In an effort to elaborate the pharmacological properties of neem, comparative study of different extracts of neem (leaves, bark and seeds) has been done. The alcoholic extracts of leaf, bark and seed in dose 100 mg/kg showed significant antinociceptive activity. The alcoholic extract of leaves (duration 240 mimutes) showed most significant analgesic activity than other extracts.