Preliminary in Vitro- Investigation on Antimicrobial Activity of Mononuclear and Dinuclear Iron (III) Complexes

Abstract

In vitro effect of two dinuclear and mononuclear iron complexes with different ligands was examined on Gram positive and Gram negative bacterial strains. Broad spectrum antibiotic oxytetracycline was used as control. The experiment was performed by the routine agar-diffusion method of bauer et al. and the method of  minimum  inhibitory concentrations (MICs). It was  found  that mononuclear complexes expressed antibacterial effect in vitro, especially against Gram (+) strains. The minimum inhibitory effect of Fe (NADP) Cl2 was more pronounced.