Biomonitoring genetic instability in normal healthy population using a simple cytogenetic marker – micronucleus test
Abstract
Micronuclei in epithelial cells are widely used as biomarkers for monitoring genetic instability in humans. In this study, we have evaluated the buccal cells of 144 normal healthy individuals. The frequency of micronuclei was analysed and their relationship to different confounding factors (age, gender, diet and life style habits) was determined. The results show a significant increase in the observed frequency of micronuclei with respect to age. Males show a comparatively high percentage of micronuclei. Non-vegetarian diet, smoking and alcohol consumption are also suggestively significant.
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Published
07-06-2011
How to Cite
Anuradha Yadav1 and Dr Rajeswari Narayanappa2, U. V. S. V. “Biomonitoring Genetic Instability in Normal Healthy Population Using a Simple Cytogenetic Marker – Micronucleus Test”. International Multidisciplinary Research Journal, vol. 1, no. 2, June 2011, https://updatepublishing.com/journal/index.php/imrj/article/view/1467.
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Section
Health Science