https://updatepublishing.com/journal/index.php/jmhe/issue/feed Journal of Medicinal Herbs and Ethnomedicine 2021-02-28T17:56:45+0530 Editorial Office contact@updatepublishing.com Open Journal Systems <p>The <strong>Journal of Medicinal Herbs and Ethnomedicine </strong>is a peer-reviewed, open access journal that publishes articles in all the in the fields of Herbal and Ethnomedicine.</p> <p>&nbsp;</p> https://updatepublishing.com/journal/index.php/jmhe/article/view/6309 Antigenotoxic potential of gel extract of Aloe vera against Sodium azide genotoxicity in Allium cepa cells 2021-02-22T13:19:15+0530 Akeem Akinboro aakinboro@lautech.edu.ng Aisha Jimoh akinboroa@yahoo.com <p style="text-align: justify;">Nowadays, the increasing rate of human exposure to various kinds of environmental mutagens has necessitated the search for natural antimutagens /antigenotoxic agents in natural products. In this study, <em>Aloe vera</em> gel extract was tested for its possible antigenotoxicity following the <em>Allium cepa</em> assay. Ten onions (<em>Allium cepa</em>) per dose were grown for 48 and 72 hours on gel extract of <em>A. vera</em> at 6.25%, 12.5%, 25.0%, 50.0% and 100.0% in combination with sodium azide (0.05mg/ml) solution for microscopic and macroscopic evaluations, respectively. Distilled water and sodium azide were the negative and positive controls, respectively. The cell division in the root tips, and root growth in the exposed <em>A. cepa</em> were inhibited in a dose dependent manner by the mixture of <em>A. vera</em> and sodium azide. However, the mixture of absolute (100.0%) dose and sodium azide completely arrested cell division and induced a lower root length than that recorded for sodium azide alone. The genotoxicity of sodium azide was inversely reduced by the doses of A. vera except at 100.0%. These results show that gel extract of <em>A. vera</em> possesses strong antigenotoxic /antimutagenic potency at lower dose range of 6.25% to 25.0% in <em>A. cepa</em> cells, however, its higher doses above 50.0% to 100.0% could be severely toxic when being considered for suppression of environmental mutagens’ mutagenicity or genotoxicity. This suggests that gel extract of <em>A. vera</em> contains phytochemical(s) that can be useful in the development of anticancer drug.</p> 2021-02-22T00:00:00+0530 Copyright (c) 2021 Akeem Akinboro, Aisha Jimoh https://updatepublishing.com/journal/index.php/jmhe/article/view/6896 A study on the use of medicinal plants for the treatment of Diarrhoea and Dysentery in Khag tehsil of District Budgam of Jammu and Kashmir 2021-02-28T17:56:45+0530 Tawseef Ahmad Mir tawseefbot@gmail.com Rakesh Kumar Khare mirt833@gmail.com Muatasim Jan muatasimbot@gmail.com <p>People are using medicinal plants to alleviate diseases since the time immemorial. The present paper enumerates a total of 25 medicinal plants belonging to 19 families used for the treatment of diarrhoea and dysentery diseases in Khag tehsil of district Budgam, Jammu and Kashmir. Asteraceae was the dominant family. Leaves were found to be dominant plant used for the preparation of herbal remedies. It was found that in this era of modern medicine, people are still relied on traditional medicine to get their primary health care. It was also revealed medicinal plants are under serious threat and needs to be conserved as so as to enjoy this legacy in future too.</p> 2021-02-28T00:00:00+0530 Copyright (c) 2021 Tawseef Ahmad Mir, Rakesh Kumar Khare, Muatasim Jan