TY - JOUR AU - Ravendra Kumar, Prakash Singh, AU - Anil Kumar Pant, Om Prakash, AU - Kumar, Mahesh AU - Lech Szczepaniak, Valary A. Isidorov, PY - 2019/02/27 Y2 - 2024/03/29 TI - Chemical Composition, Anti-inflammatory, Analgesic, Antipyretic, Myorelaxant, Antibacterial and Antifungal activity of Rabdosia rugosus Wall. (Syn. Plectranthus rugosus Wall.) JF - Journal of Medicinal Herbs and Ethnomedicine JA - JMHE VL - 5 IS - 0 SE - Articles DO - 10.25081/jmhe.2019.v5.3831 UR - https://updatepublishing.com/journal/index.php/jmhe/article/view/3831 SP - 08-15 AB - <p>For the present investigation Rabdosia rugosus Wall. Syn. Plectranthus rugosus Wall.&nbsp; was collected from Pancheshwar, Uttarakhand on the way to Badrinath. The GC and GC-MS analysis, revealed the presence of more than forty compounds out of which 35 compounds were identified amounting to 97.3% of the total oil. The essential oil of R. rugosus was rich in sesquiterpinoids (~90%) and was poor in monoterpenoids (8.1%). α-bisabolol (41.9%) was the major constituent of the oil and the other identified major compounds were germacrene-D (9.7%), β-caryophyllene (7.6%), dehydroabietane (5.2%), ar-curcumene (5.0), trans-ferruginol (3.3%) α-cadinol (3.2%), τ-muurolol (2.3%), &nbsp;&nbsp;p-Cymene (3.2%) and&nbsp; γ-terpinene (2.0%). The&nbsp; essential&nbsp; oil&nbsp; of&nbsp; Rabdosia rugosus showed insignificant&nbsp; anti-inflammatory&nbsp; and&nbsp; analgesic&nbsp; activity&nbsp; but&nbsp; shows&nbsp; significant&nbsp; antipyretic,&nbsp; &nbsp;myorelaxant and &nbsp;antimicrobial activity.</p> ER -